在这项研究中，将放射学方法扩展到用于组织分类的光学荧光分子成像数据，称为“验光”。荧光分子成像正在出现在头颈部鳞状细胞癌（HNSCC）切除期间的精确手术引导。然而，肿瘤到正常的组织对比与靶分子表皮生长因子受体（EGFR）的异质表达的内在生理局限性混淆。验光学试图通过探测荧光传达的EGFR表达中的质地模式差异来改善肿瘤识别。从荧光图像样品中提取了总共1,472个标准化的验光特征。涉及支持矢量机分类器的监督机器学习管道接受了25个顶级功能的培训，这些功能由最小冗余最大相关标准选择。通过将切除组织的图像贴片分类为组织学确认的恶性肿瘤状态，将模型预测性能与荧光强度阈值方法进行了比较。与荧光强度阈值方法相比，验光方法在所有测试集样品中提供了一致的预测准确性（无剂量）（平均精度为89％vs. 81％； P = 0.0072）。改进的性能表明，将放射线学方法扩展到荧光分子成像数据为荧光引导手术中的癌症检测提供了有希望的图像分析技术。

Recent advances in deep learning have enabled us to address the curse of dimensionality (COD) by solving problems in higher dimensions. A subset of such approaches of addressing the COD has led us to solving high-dimensional PDEs. This has resulted in opening doors to solving a variety of real-world problems ranging from mathematical finance to stochastic control for industrial applications. Although feasible, these deep learning methods are still constrained by training time and memory. Tackling these shortcomings, Tensor Neural Networks (TNN) demonstrate that they can provide significant parameter savings while attaining the same accuracy as compared to the classical Dense Neural Network (DNN). In addition, we also show how TNN can be trained faster than DNN for the same accuracy. Besides TNN, we also introduce Tensor Network Initializer (TNN Init), a weight initialization scheme that leads to faster convergence with smaller variance for an equivalent parameter count as compared to a DNN. We benchmark TNN and TNN Init by applying them to solve the parabolic PDE associated with the Heston model, which is widely used in financial pricing theory.

Managing novelty in perception-based human activity recognition (HAR) is critical in realistic settings to improve task performance over time and ensure solution generalization outside of prior seen samples. Novelty manifests in HAR as unseen samples, activities, objects, environments, and sensor changes, among other ways. Novelty may be task-relevant, such as a new class or new features, or task-irrelevant resulting in nuisance novelty, such as never before seen noise, blur, or distorted video recordings. To perform HAR optimally, algorithmic solutions must be tolerant to nuisance novelty, and learn over time in the face of novelty. This paper 1) formalizes the definition of novelty in HAR building upon the prior definition of novelty in classification tasks, 2) proposes an incremental open world learning (OWL) protocol and applies it to the Kinetics datasets to generate a new benchmark KOWL-718, 3) analyzes the performance of current state-of-the-art HAR models when novelty is introduced over time, 4) provides a containerized and packaged pipeline for reproducing the OWL protocol and for modifying for any future updates to Kinetics. The experimental analysis includes an ablation study of how the different models perform under various conditions as annotated by Kinetics-AVA. The protocol as an algorithm for reproducing experiments using the KOWL-718 benchmark will be publicly released with code and containers at https://github.com/prijatelj/human-activity-recognition-in-an-open-world. The code may be used to analyze different annotations and subsets of the Kinetics datasets in an incremental open world fashion, as well as be extended as further updates to Kinetics are released.

FSS(Few-shot segmentation)~aims to segment a target class with a small number of labeled images (support Set). To extract information relevant to target class, a dominant approach in best performing FSS baselines removes background features using support mask. We observe that this support mask presents an information bottleneck in several challenging FSS cases e.g., for small targets and/or inaccurate target boundaries. To this end, we present a novel method (MSI), which maximizes the support-set information by exploiting two complementary source of features in generating super correlation maps. We validate the effectiveness of our approach by instantiating it into three recent and strong FSS baselines. Experimental results on several publicly available FSS benchmarks show that our proposed method consistently improves the performance by visible margins and allows faster convergence. Our codes and models will be publicly released.

Large language models (LLMs) have been shown to be able to perform new tasks based on a few demonstrations or natural language instructions. While these capabilities have led to widespread adoption, most LLMs are developed by resource-rich organizations and are frequently kept from the public. As a step towards democratizing this powerful technology, we present BLOOM, a 176B-parameter open-access language model designed and built thanks to a collaboration of hundreds of researchers. BLOOM is a decoder-only Transformer language model that was trained on the ROOTS corpus, a dataset comprising hundreds of sources in 46 natural and 13 programming languages (59 in total). We find that BLOOM achieves competitive performance on a wide variety of benchmarks, with stronger results after undergoing multitask prompted finetuning. To facilitate future research and applications using LLMs, we publicly release our models and code under the Responsible AI License.

我们介绍了一种考虑复杂的环境条件，在极地地区介绍了一种在极地地区长距离海上路线计划的方法。该方法允许构建优化的路线，描述了该过程的三个主要阶段：使用不均匀网格对环境条件进行离散建模，网格最佳路径的构建以及路径平滑。为了说明不同的车辆性能，我们构建了一系列数据驱动的功能，这些功能可以应用于环境网格，以确定给定容器和网格单元的速度限制和燃料要求，以图形和地理空间表示这些数量。在描述我们的结果时，我们展示了一个示例用途，用于Polar Research船RRS David Attenborough爵士（SDA）的路线规划，核算冰的性能特征，并验证韦德尔海地区的时空路线构建，南极洲。我们通过证明路线的变化取决于季节性海冰可变性，所使用的路线规划目标函数的差异以及其他环境条件（如电流）的存在来证明这种路线构建方法的多功能性。为了证明我们的方法的普遍性，我们在北极海洋和波罗的海中介绍了例子。本手稿中概述的技术是通用的，因此可以应用于具有不同特征的血管。我们的方法不仅可以拥有一个船只计划程序，而且我们概述了该工作流程如何适用于更广泛的社区，例如商业和乘客运输。

本文提出了一种延时3D细胞分析的方法。具体而言，我们考虑了准确定位和定量分析亚细胞特征的问题，以及从延时3D共聚焦细胞图像堆栈跟踪单个细胞的问题。细胞的异质性和多维图像的体积提出了对细胞形态发生和发育的完全自动化分析的主要挑战。本文是由路面细胞生长过程和构建定量形态发生模型的动机。我们提出了一种基于深度特征的分割方法，以准确检测和标记每个细胞区域。基于邻接图的方法用于提取分段细胞的亚细胞特征。最后，提出了使用多个单元格特征的基于强大的图形跟踪算法在不同的时间实例中关联单元格。提供了广泛的实验结果，并证明了所提出的方法的鲁棒性。该代码可在GitHub上获得，该方法可通过Bisque Portal作为服务可用。

部分微分方程（PDE）用于对科学和工程中的各种动力系统进行建模。深度学习的最新进展使我们能够以新的方式解决维度的诅咒，从而在更高的维度中解决它们。但是，深度学习方法受到训练时间和记忆的约束。为了解决这些缺点，我们实施了张量神经网络（TNN），这是一种量子启发的神经网络体系结构，利用张量网络的想法来改进深度学习方法。我们证明，与经典密集神经网络（DNN）相比，TNN提供了明显的参数节省，同时获得了与经典密集的神经网络相同的准确性。此外，我们还展示了如何以相同的精度来比DNN更快地训练TNN。我们通过将它们应用于求解抛物线PDE，特别是Black-Scholes-Barenblatt方程，该方程广泛用于金融定价理论，基于基准测试。还讨论了进一步的例子，例如汉密尔顿 - 雅各比 - 贝尔曼方程。

深度均衡网络（DEQ）是构建模型以进行计算的模型的一种有希望的方法。但是，与传统网络相比，对这些模型的理论理解仍然缺乏，部分原因是一组重量的重复应用。我们表明，DEQ对初始化的基质家族的高阶统计敏感。特别是，用正交或对称矩阵初始化可以在训练中提高稳定性。这为我们提供了初始化的实用处方，该处方允许以更广泛的初始重量量表进行训练。

{g} {ustav} Fechner 1860年的心理物理学描述，即对其刺激的感觉的测量，被广泛认为是现代心理科学的出现。在心理物理学中，研究人员的参数会改变刺激的某些方面，并衡量人类受试者对该刺激的经历的变化；这样做可以深入了解感觉与唤起它的物理输入之间的关系。这种方法在感知域中大量使用，包括信号检测，阈值测量和理想的观察者分析。像视觉科学这样的科学领域始终依靠心理物理学的方法和程序，但是现在，机器学习研究人员对它们的越来越多，通过在生物学和人工感知之间扩大重叠\ cite \ cite {rojas2011automation {scheireratom，scheirer2014Perceptial2014Perceptual，Escalera2014ChaleAr2014Chalearearearearearnnag，Zhangy2018Agic， grieggs2021measuring}。由行为测量所指导的机器感知，而不是仅限于任意分配人类标签的指导，具有为人工智能进一步进步的巨大潜力。